Immune System Functions Activities for Middle School Science

Explore the immune system’s role in maintaining health with this engaging 5E lesson designed for TEKS 7.13A. Students begin with interactive activities like word wall cards and discussions before diving into a hands-on station lab covering immune system functions, key organs, and diseases. Through reading passages, experiments, videos, writing prompts, and categorization activities, students actively engage with the content. The lesson includes editable PowerPoints, interactive notebooks, and note-taking templates for guided instruction. Students extend their learning with choice projects, while assessments aligned to STAAR 2.0 ensure comprehension. Available in print and digital formats, with Spanish translations, this flexible resource supports diverse learners in both in-class and virtual settings. The resources below will give students a comprehensive understanding of the immune system. All of the following materials are also included in the Kesler Science Membership.

The Kesler Science Immune System 5E Lesson is a comprehensive, student-led unit designed to explore the role of the immune system in maintaining health. It includes editable PowerPoints, worksheets, choice projects, and assessments, with differentiated and multimodal resources for diverse learners. The lesson aligns with the 2021 TEKS 7.13A standard and is available in both print and digital formats, with Spanish translations for key materials.

Following the 5E Model, the lesson begins with engagement activities, including word wall cards and class discussions. The exploration phase features a hands-on, student-led station lab with nine stations covering immune system functions, key organs, and related diseases. Students engage with content through reading passages, experiments, research, videos, categorization activities, writing prompts, illustrations, and assessments. An optional challenge station provides extension activities.

The explanation phase includes editable PowerPoints, interactive notebooks, and note-taking templates. Students elaborate on their learning through choice projects, while evaluation includes STAAR 2.0-aligned assessments, review worksheets, and test practice. Designed for flexibility, the lesson supports in-class and virtual learning, making it an engaging and adaptable resource for middle school science classrooms.

Engage your middle school students with this student-led station lab aligned with TEKS 7.13A, focusing on immune system functions. Designed for in-class or virtual learning, this interactive lesson allows students to explore and model key immune system functions through nine differentiated stations featuring videos, readings, research, and hands-on tasks.

Students demonstrate their learning by organizing information, illustrating models, writing responses, and completing assessments. A bonus challenge station offers extension activities, and English and Spanish reading passages support differentiated learning. This low-prep, high-engagement resource promotes active learning and critical thinking.

The Immune System Functions Student Choice Projects align with the 2021 TEKS standard 7.13A, giving middle school students the flexibility to choose a project that matches their preferred output style. A project page outlines six student-led options plus a “design your own” project, all supported by an editable rubric for teacher, peer, or self-assessment. This resource is also included in the Immune System Functions Complete Lesson for TEKS 7.13A.

These multimodal projects allow students to showcase their understanding in creative ways. Two versions of the project page support differentiation, with modified options for students needing remediation and challenge opportunities for advanced learners. Teachers can adjust the rubric to fit grading needs.

The projects use common classroom supplies such as paper, markers, and scissors, with many options available for digital completion.

Year-Round Resources

These year-round activities will increase your students' understanding of many middle school science topics. All of these activities are also included in the Kesler Science Membership.

Visual Data & Graphing

You're not alone if your students struggle with understanding graphs, charts, and tables. It's a skill that takes an enormous amount of practice. This resource will help students build a strong foundation in analyzing data and creating their own data visualizations.

Learn More

Bell Ringers and Warm-Ups

These middle school science bell ringers are an excellent way to engage your students as soon as they walk into your classroom. This comprehensive FULL YEAR resource includes everything you need to start off each science class with an interesting warm-up activity.

Learn More

Review Board Games

Each game board has been carefully designed to keep students engaged. There are 10 different action spaces on each board and dozens of question cards. All of the actions are related to science concepts and keep the students motivated throughout the game.

Each game is ready to play. Simply print out the board and the cards and let the students enjoy reviewing nine different units.

Learn More

Essential Questions and Standards

Below are the essential questions and standards associated with the lessons and activities included in the atoms unit. This topic is only one of more than 100 middle school science topics included in the Kesler Science Membership.

Essential Questions

What are the main organs and tissues found in the human immune system?
How do these organs and tissues work to keep us from getting sick?

Standards

TEKS Science - 7.13A Immune System Functions