Endocrine System Activities for Middle School Science
The Kesler Science Endocrine System Resources provide a comprehensive, student-centered lesson for middle school students, featuring differentiated materials, multimodal activities, and both printable and digital formats. The resources below will give students a comprehensive understanding of the endocrine system. All of the following materials are also included in the Kesler Science Membership.
The Kesler Science Endocrine System Complete 5E Lesson makes lesson planning simple with everything you need to teach an engaging, multi-day lesson. Designed for 6th to 8th-grade students, this resource offers differentiated materials to cater to various learning needs, helping students understand the structure and function of the endocrine system. The lesson includes flexible formats—printable and digital—and Spanish translations, making it adaptable for diverse classrooms.
This comprehensive lesson follows the 5E Model: Engagement, Exploration, Explanation, Elaboration, and Evaluation. Students explore nine differentiated stations, including hands-on demos, reading passages, research activities, and videos. These stations offer multimodal ways for students to absorb and demonstrate their learning through activities like card sorting, writing, and drawing. The Challenge It! station offers additional activities for early finishers.
Assessment is built into the lesson with editable PowerPoints, interactive notebook templates, and a variety of evaluation options. The resource is designed for both in-person and virtual learning, with tools like Google Slides and PowerPoint, ensuring accessibility for all students.
The Kesler Science Endocrine System Complete 5E Lesson makes lesson planning simple with everything you need to teach an engaging, multi-day lesson. Designed for 6th to 8th-grade students, this resource offers differentiated materials to cater to various learning needs, helping students understand the structure and function of the endocrine system. The lesson includes flexible formats—printable and digital—and Spanish translations, making it adaptable for diverse classrooms.
This comprehensive lesson follows the 5E Model: Engagement, Exploration, Explanation, Elaboration, and Evaluation. Students explore nine differentiated stations, including hands-on demos, reading passages, research activities, and videos. These stations offer multimodal ways for students to absorb and demonstrate their learning through activities like card sorting, writing, and drawing. The Challenge It! station offers additional activities for early finishers.
Assessment is built into the lesson with editable PowerPoints, interactive notebook templates, and a variety of evaluation options. The resource is designed for both in-person and virtual learning, with tools like Google Slides and PowerPoint, ensuring accessibility for all students.
The Kesler Science Endocrine System Station Lab provides a student-led, modular approach to learning that keeps middle school students engaged while exploring the functions of the endocrine system and its role in maintaining homeostasis. With differentiated activities and a challenge station for advanced learners, this lesson allows students to take charge of their own learning experience.
The nine stations offer diverse, multimodal activities to introduce and reinforce key concepts. Students can explore the system through hands-on demonstrations, research, reading, and videos, followed by output stations where they organize, illustrate, and write about their newfound knowledge. The challenge station extends learning for early finishers.
Designed for flexibility, the station lab works well in both in-person and virtual environments. Teachers can use this resource to facilitate student learning with minimal prep, making it ideal for a variety of classroom settings.
The Kesler Science Endocrine System Station Lab provides a student-led, modular approach to learning that keeps middle school students engaged while exploring the functions of the endocrine system and its role in maintaining homeostasis. With differentiated activities and a challenge station for advanced learners, this lesson allows students to take charge of their own learning experience.
The nine stations offer diverse, multimodal activities to introduce and reinforce key concepts. Students can explore the system through hands-on demonstrations, research, reading, and videos, followed by output stations where they organize, illustrate, and write about their newfound knowledge. The challenge station extends learning for early finishers.
Designed for flexibility, the station lab works well in both in-person and virtual environments. Teachers can use this resource to facilitate student learning with minimal prep, making it ideal for a variety of classroom settings.
The Kesler Science Endocrine System Student Choice Projects offer middle school students the opportunity to select a project that aligns with their learning preferences. With six project options and a "design your own" choice, students can creatively demonstrate their understanding of the endocrine system. A customizable grading rubric allows for assessments by teachers, peers, or self-assessment.
This flexible resource includes nine project options and an editable rubric that focuses on vocabulary, concepts, presentation, and accuracy. The Student Choice Projects cater to a range of learning styles and can be modified to suit students needing remediation or additional challenges. Teachers can assign a mix of projects while using the same rubric for consistency.
Materials for the projects are minimal, utilizing standard classroom supplies like paper, markers, and scissors, while some projects can be done digitally. For hands-on projects, basic crafting supplies may be helpful, but many activities are adaptable to both in-person and virtual learning environments.
The Kesler Science Endocrine System Student Choice Projects offer middle school students the opportunity to select a project that aligns with their learning preferences. With six project options and a "design your own" choice, students can creatively demonstrate their understanding of the endocrine system. A customizable grading rubric allows for assessments by teachers, peers, or self-assessment.
This flexible resource includes nine project options and an editable rubric that focuses on vocabulary, concepts, presentation, and accuracy. The Student Choice Projects cater to a range of learning styles and can be modified to suit students needing remediation or additional challenges. Teachers can assign a mix of projects while using the same rubric for consistency.
Materials for the projects are minimal, utilizing standard classroom supplies like paper, markers, and scissors, while some projects can be done digitally. For hands-on projects, basic crafting supplies may be helpful, but many activities are adaptable to both in-person and virtual learning environments.
The Kesler Science Body Systems Interactive Notebook Bundle provides a hands-on and engaging way for students to learn about body systems, offering both print and digital options for flexible use in traditional classrooms, 1:1 settings, or distance learning environments. Students can explore key systems, such as the circulatory, digestive, and nervous systems, while interacting with customized templates and reflection pages to enhance understanding.
The digital version features an interactive PowerPoint file that can be uploaded to Google Slides or other platforms like MS Teams or Canvas, making it easy to assign and complete remotely. Students can add notes, complete reflection activities, and access modified templates as needed. The teacher key and modified digital versions ensure accessibility for all learners.
The paper version includes blank and pre-filled templates, along with color photos for guidance, making it ideal for interactive notebooks. This comprehensive bundle offers everything teachers need to support students’ mastery of body system concepts while catering to diverse learning needs.
The Kesler Science Body Systems Interactive Notebook Bundle provides a hands-on and engaging way for students to learn about body systems, offering both print and digital options for flexible use in traditional classrooms, 1:1 settings, or distance learning environments. Students can explore key systems, such as the circulatory, digestive, and nervous systems, while interacting with customized templates and reflection pages to enhance understanding.
The digital version features an interactive PowerPoint file that can be uploaded to Google Slides or other platforms like MS Teams or Canvas, making it easy to assign and complete remotely. Students can add notes, complete reflection activities, and access modified templates as needed. The teacher key and modified digital versions ensure accessibility for all learners.
The paper version includes blank and pre-filled templates, along with color photos for guidance, making it ideal for interactive notebooks. This comprehensive bundle offers everything teachers need to support students’ mastery of body system concepts while catering to diverse learning needs.
The Kesler Science Endocrine System Inquiry Lab offers an engaging and flexible lab experience for students to explore the functions of the endocrine system and understand how glands and hormones work together to maintain homeostasis. Students will learn how hormones act like keys that fit into specific receptors, modeled with puzzle pieces. Both virtual and hands-on versions guide students through the concept of a negative feedback loop using interactive activities and physical demonstrations.
This lab includes three differentiated versions—Modified, Dependent, and Independent—allowing teachers to meet the needs of all learners. Each version includes comprehension questions, C.E.R. prompts, and reflection sections to encourage critical thinking. The print version uses classroom materials such as puzzle pieces, play sand, and a graduated cylinder, while the digital version includes an interactive lab file and a pre-recorded video that walks students through the experiment.
Designed for maximum flexibility, the resource features editable PowerPoints, Google Slides compatibility, and complete teacher support materials including answer keys, lab instructions, and prep guides. With both digital and print options available, teachers can adapt this lab to suit in-person, virtual, or hybrid classrooms.
The Kesler Science Endocrine System Inquiry Lab offers an engaging and flexible lab experience for students to explore the functions of the endocrine system and understand how glands and hormones work together to maintain homeostasis. Students will learn how hormones act like keys that fit into specific receptors, modeled with puzzle pieces. Both virtual and hands-on versions guide students through the concept of a negative feedback loop using interactive activities and physical demonstrations.
This lab includes three differentiated versions—Modified, Dependent, and Independent—allowing teachers to meet the needs of all learners. Each version includes comprehension questions, C.E.R. prompts, and reflection sections to encourage critical thinking. The print version uses classroom materials such as puzzle pieces, play sand, and a graduated cylinder, while the digital version includes an interactive lab file and a pre-recorded video that walks students through the experiment.
Designed for maximum flexibility, the resource features editable PowerPoints, Google Slides compatibility, and complete teacher support materials including answer keys, lab instructions, and prep guides. With both digital and print options available, teachers can adapt this lab to suit in-person, virtual, or hybrid classrooms.
The Kesler Science Body Systems Sub Plans guide students through an engaging sequence of activities, including a warm-up puzzle, a reading passage, and a hands-on project to create a booklet labeling the organs and functions of each body system. Using their booklets, students answer questions to deepen their understanding. Extension activities challenge early finishers to explore how systems like the skeletal and muscular systems work together or how multiple systems collaborate to digest a meal. The lesson concludes with an assessment or exit ticket.
Comprehensive support is provided for both in-class and distance learning formats, including substitute teacher instructions, a Google Form answer sheet, and editable resources. Each lesson is thoughtfully crafted to minimize downtime, with substitute directions, behavior checkpoints, and engaging activities to ensure a productive day. Digital versions allow students to annotate PDFs or submit answers online, making the resource versatile for remote or in-person use.
These middle school science sub plans are perfect for days when teachers are out, offering clear instructions for substitutes and meaningful, student-centered activities. They are also ideal for homework, extra credit, or small group sessions. Packed with editable documents, answer keys, and flexible learning formats, these plans make managing classroom learning seamless and stress-free.
The Kesler Science Body Systems Sub Plans guide students through an engaging sequence of activities, including a warm-up puzzle, a reading passage, and a hands-on project to create a booklet labeling the organs and functions of each body system. Using their booklets, students answer questions to deepen their understanding. Extension activities challenge early finishers to explore how systems like the skeletal and muscular systems work together or how multiple systems collaborate to digest a meal. The lesson concludes with an assessment or exit ticket.
Comprehensive support is provided for both in-class and distance learning formats, including substitute teacher instructions, a Google Form answer sheet, and editable resources. Each lesson is thoughtfully crafted to minimize downtime, with substitute directions, behavior checkpoints, and engaging activities to ensure a productive day. Digital versions allow students to annotate PDFs or submit answers online, making the resource versatile for remote or in-person use.
These middle school science sub plans are perfect for days when teachers are out, offering clear instructions for substitutes and meaningful, student-centered activities. They are also ideal for homework, extra credit, or small group sessions. Packed with editable documents, answer keys, and flexible learning formats, these plans make managing classroom learning seamless and stress-free.
The Kesler Science Body Systems Escape Room provides an immersive, hands-on way for students to demonstrate their understanding of major body systems, their structures, and their functions. With eight unique puzzles, teachers have full control over the activities, choosing which puzzles to use and their order—perfect for adapting to different class lengths. This engaging activity combines critical thinking, teamwork, and science content into a memorable classroom experience.
The escape room can be run using simple materials like manila envelopes or with more authentic props, including locks and a storage box, for a realistic feel. Both physical and digital versions are available, offering flexibility for in-person or virtual learning. Digital versions include editable PowerPoints and Google Slides, while printable materials support at-home or classroom setups. Tools like UV pens, red cellophane, and mirrors add to the fun, but alternatives are provided for cost-effective implementation.
The product includes everything needed for a smooth experience: teacher directions, a detailed answer key, a digital answer sheet, editable templates, a mood-setting video challenge, printable props, reward templates, and over 50 prize ideas. Whether used in a physical or digital format, the Kesler Science Escape Room is an engaging and versatile resource for reinforcing body systems knowledge.
The Kesler Science Body Systems Escape Room provides an immersive, hands-on way for students to demonstrate their understanding of major body systems, their structures, and their functions. With eight unique puzzles, teachers have full control over the activities, choosing which puzzles to use and their order—perfect for adapting to different class lengths. This engaging activity combines critical thinking, teamwork, and science content into a memorable classroom experience.
The escape room can be run using simple materials like manila envelopes or with more authentic props, including locks and a storage box, for a realistic feel. Both physical and digital versions are available, offering flexibility for in-person or virtual learning. Digital versions include editable PowerPoints and Google Slides, while printable materials support at-home or classroom setups. Tools like UV pens, red cellophane, and mirrors add to the fun, but alternatives are provided for cost-effective implementation.
The product includes everything needed for a smooth experience: teacher directions, a detailed answer key, a digital answer sheet, editable templates, a mood-setting video challenge, printable props, reward templates, and over 50 prize ideas. Whether used in a physical or digital format, the Kesler Science Escape Room is an engaging and versatile resource for reinforcing body systems knowledge.
The Kesler Science Endocrine System Reading Comprehension lesson allows middle school students to study the human endocrine system through an engaging nonfiction article. Students will explore the system's structures and functions, answer comprehension questions, and creatively express their learning by writing a song or poem. This lesson is designed to boost both science literacy and reading comprehension.
The resource includes two leveled articles with Lexile levels ranging from 1100-1300, each paired with 5-7 comprehension questions and a hands-on mini-project. A Cornell notes template is also provided to support students in organizing key concepts. With colorful graphics and printable or digital versions, this activity is accessible for both in-person and virtual learning environments.
Perfect for a range of uses, this resource supports differentiated instruction, making it ideal for absent students, extra credit, and whole-class activities. The leveled passages foster science literacy, promote critical thinking, and spark classroom discussions, making this a valuable tool for building students’ textual analysis and comprehension skills in science.
The Kesler Science Endocrine System Reading Comprehension lesson allows middle school students to study the human endocrine system through an engaging nonfiction article. Students will explore the system's structures and functions, answer comprehension questions, and creatively express their learning by writing a song or poem. This lesson is designed to boost both science literacy and reading comprehension.
The resource includes two leveled articles with Lexile levels ranging from 1100-1300, each paired with 5-7 comprehension questions and a hands-on mini-project. A Cornell notes template is also provided to support students in organizing key concepts. With colorful graphics and printable or digital versions, this activity is accessible for both in-person and virtual learning environments.
Perfect for a range of uses, this resource supports differentiated instruction, making it ideal for absent students, extra credit, and whole-class activities. The leveled passages foster science literacy, promote critical thinking, and spark classroom discussions, making this a valuable tool for building students’ textual analysis and comprehension skills in science.
The Kesler Science Endocrine System Science Writing Prompt Activity provides middle school students with an engaging, interview-based exercise to test their knowledge of life science. This creative, low-prep activity promotes science reasoning and enhances student writing, with materials that are perfect for both in-class and virtual learning environments. The prompt encourages students to delve into the topic of the endocrine system while refining their communication skills.
Included in this resource are teacher directions with an answer guide, project ideas, and customizable rubrics. Students can choose from full-sized handouts, half-sheet options for journals, and a digital interactive version that is easily adaptable for Google Slides. This flexible format supports a variety of learning styles and assessment needs.
The Endocrine System Writing Prompt can be used for a range of purposes such as pre-test formative assessments, student choice projects, extra credit, or make-up work. Its adaptable structure also makes it ideal for differentiation and cross-curricular activities, ensuring all students can participate and grow in their understanding of the endocrine system.
The Kesler Science Endocrine System Science Writing Prompt Activity provides middle school students with an engaging, interview-based exercise to test their knowledge of life science. This creative, low-prep activity promotes science reasoning and enhances student writing, with materials that are perfect for both in-class and virtual learning environments. The prompt encourages students to delve into the topic of the endocrine system while refining their communication skills.
Included in this resource are teacher directions with an answer guide, project ideas, and customizable rubrics. Students can choose from full-sized handouts, half-sheet options for journals, and a digital interactive version that is easily adaptable for Google Slides. This flexible format supports a variety of learning styles and assessment needs.
The Endocrine System Writing Prompt can be used for a range of purposes such as pre-test formative assessments, student choice projects, extra credit, or make-up work. Its adaptable structure also makes it ideal for differentiation and cross-curricular activities, ensuring all students can participate and grow in their understanding of the endocrine system.
The Kesler Science WIKI Tickets provide engaging, flexible formative assessments for 6th–8th grade science topics, designed to check student understanding in a fun and interactive way. Aligned with NGSS and TEKS standards, these assessments cover nine body systems, including the circulatory, digestive, endocrine, excretory, muscular, nervous, respiratory, and skeletal systems, as well as sensory information. Each topic includes five formats: projection, full-page, split-page, quarter-page handouts, and editable digital versions for use in PowerPoint or Google Slides.
These colorful WIKI Tickets can be used as exit tickets, bellringers, or quick checks for learning progress. Teachers have the flexibility to use them in print, project them for whole-class responses, or assign them digitally for 1:1 and virtual settings. A bonus table of contents file shows the alignment of each ticket to middle school science standards, ensuring comprehensive coverage of key concepts.
Perfect for both in-person and remote learning, the WIKI Tickets make lesson planning easier while keeping students engaged and on track. These versatile tools ensure you're prepared to assess understanding in any learning environment.
The Kesler Science WIKI Tickets provide engaging, flexible formative assessments for 6th–8th grade science topics, designed to check student understanding in a fun and interactive way. Aligned with NGSS and TEKS standards, these assessments cover nine body systems, including the circulatory, digestive, endocrine, excretory, muscular, nervous, respiratory, and skeletal systems, as well as sensory information. Each topic includes five formats: projection, full-page, split-page, quarter-page handouts, and editable digital versions for use in PowerPoint or Google Slides.
These colorful WIKI Tickets can be used as exit tickets, bellringers, or quick checks for learning progress. Teachers have the flexibility to use them in print, project them for whole-class responses, or assign them digitally for 1:1 and virtual settings. A bonus table of contents file shows the alignment of each ticket to middle school science standards, ensuring comprehensive coverage of key concepts.
Perfect for both in-person and remote learning, the WIKI Tickets make lesson planning easier while keeping students engaged and on track. These versatile tools ensure you're prepared to assess understanding in any learning environment.
The Kesler Science Body Systems Lesson Extensions provide student-choice activities designed to challenge early finishers and deepen their understanding of body systems through engaging, creative, and rigorous learning opportunities. These activities are perfect for ending lessons, filling testing gaps, or keeping students focused with NGSS- and TEKS-aligned content. Students can explore critical thinking and creativity through puzzles, STEAM-based maker activities, digital media projects, and creative writing tasks.
Each extension includes teacher directions, answer keys, projection options for digital boards, and printable handouts in full- and half-sheet formats. Topics covered include the circulatory, digestive, endocrine, excretory, integumentary, muscular, nervous, respiratory, and skeletal systems, as well as sensory information, making them a perfect supplement for anatomy and physiology units.
Kesler Science Lesson Extensions help scaffold learning for independent learners, offering a variety of high-level activities to enhance problem-solving, creativity, and hands-on engagement, all while maintaining alignment with key science standards.
The Kesler Science Body Systems Lesson Extensions provide student-choice activities designed to challenge early finishers and deepen their understanding of body systems through engaging, creative, and rigorous learning opportunities. These activities are perfect for ending lessons, filling testing gaps, or keeping students focused with NGSS- and TEKS-aligned content. Students can explore critical thinking and creativity through puzzles, STEAM-based maker activities, digital media projects, and creative writing tasks.
Each extension includes teacher directions, answer keys, projection options for digital boards, and printable handouts in full- and half-sheet formats. Topics covered include the circulatory, digestive, endocrine, excretory, integumentary, muscular, nervous, respiratory, and skeletal systems, as well as sensory information, making them a perfect supplement for anatomy and physiology units.
Kesler Science Lesson Extensions help scaffold learning for independent learners, offering a variety of high-level activities to enhance problem-solving, creativity, and hands-on engagement, all while maintaining alignment with key science standards.
The Body Systems Card Sort activity helps students learn about the ten major human body systems by sorting them based on their system name, main function, and major organs. This engaging activity can be used during instruction, as a review game, or for intervention and tutoring, providing a fun alternative to traditional study methods.
The body systems included are circulatory, skeletal, endocrine, muscular, integumentary, nervous, digestive, excretory, respiratory, and reproductive. This resource is suitable for any middle school students studying body systems.
The Body Systems Card Sort activity helps students learn about the ten major human body systems by sorting them based on their system name, main function, and major organs. This engaging activity can be used during instruction, as a review game, or for intervention and tutoring, providing a fun alternative to traditional study methods.
The body systems included are circulatory, skeletal, endocrine, muscular, integumentary, nervous, digestive, excretory, respiratory, and reproductive. This resource is suitable for any middle school students studying body systems.
The Amazing Anchors Phenomenon Lesson introduces and reinforces the endocrine system through the real-world example of Robert Wadlow and his record-breaking height. Students begin with an engaging introductory reading followed by comprehension and extension questions that prepare them for deeper exploration. The second part of the lesson features an explanatory reading that breaks down the science behind the endocrine system and hormone production, helping students build a clearer understanding of this complex system.
This no-prep resource includes teacher directions with answer keys, full-page projection slides, and both digital and print formats with editable PowerPoint files. It comes with full- and half-sheet handouts, ideal for interactive notebooks. Differentiated versions are also included, offering sentence starters and simplified language to support a range of learners.
Designed to bookend any endocrine system lesson, these materials are perfect for the Engagement and Elaborate phases of a 5E model. Whether used in-person or virtually, this resource encourages students to make real-world connections and supports content retention through meaningful reading-based activities.
The Amazing Anchors Phenomenon Lesson introduces and reinforces the endocrine system through the real-world example of Robert Wadlow and his record-breaking height. Students begin with an engaging introductory reading followed by comprehension and extension questions that prepare them for deeper exploration. The second part of the lesson features an explanatory reading that breaks down the science behind the endocrine system and hormone production, helping students build a clearer understanding of this complex system.
This no-prep resource includes teacher directions with answer keys, full-page projection slides, and both digital and print formats with editable PowerPoint files. It comes with full- and half-sheet handouts, ideal for interactive notebooks. Differentiated versions are also included, offering sentence starters and simplified language to support a range of learners.
Designed to bookend any endocrine system lesson, these materials are perfect for the Engagement and Elaborate phases of a 5E model. Whether used in-person or virtually, this resource encourages students to make real-world connections and supports content retention through meaningful reading-based activities.
Year-Round Resources
These year-round activities will increase your students' understanding of many middle school science topics. All of these activities are also included in the Kesler Science Membership.
Visual Data & Graphing
You're not alone if your students struggle with understanding graphs, charts, and tables. It's a skill that takes an enormous amount of practice. This resource will help students build a strong foundation in analyzing data and creating their own data visualizations.
Bell Ringers and Warm-Ups
These middle school science bell ringers are an excellent way to engage your students as soon as they walk into your classroom. This comprehensive FULL YEAR resource includes everything you need to start off each science class with an interesting warm-up activity.
Review Board Games
Each game board has been carefully designed to keep students engaged. There are 10 different action spaces on each board and dozens of question cards. All of the actions are related to science concepts and keep the students motivated throughout the game.
Each game is ready to play. Simply print out the board and the cards and let the students enjoy reviewing nine different units.
Essential Questions
Below are the essential questions associated with the lessons and activities included in this unit. This topic is only one of more than 100 middle school science topics included in the Kesler Science Membership.
-
What is the main function of the endocrine system and how is it structured?
-
What are the main organs associated with this system?
Kesler Science Membership
Imagine never having to search for another middle school science lesson again. The membership gives you access to ALL of the Kesler Science products in one place (Yes, including everything above).
Say goodbye to long hours of lesson prep.